2016 Research Updates
November 27, 2016 - The 2016 KDA conference research PowerPoint presentations are below.
Understanding KD - Dr. Cynthia Jordan
Update from the NIH on KD - Dr. Kurt Fischbeck
Androgen Receptor Modifications - Dr. Janghoo Lim
Therapeutics Development for KD - Dr. Kurt Fischbeck
Excercise in KD - Dr. Christopher Grunseich
Pain Management in KD - Dr. Raghav Govindarajan
August 6, 2016 - SMA Drug Trial Goes So Well It Ends Early. This Los Angeles Times article on a new treatment for SMA Type 1 is very promising news and it might lead to additional breakthroughs for Type 2, 3 and 4. SMA is different then SBMA (Kennedy's Disease), but antisense technology is being used in other progressive disorders. To read the article, click here.
July 29, 2016 - Dr. Chris Grünseich, NIH Clinical Fellow, discuss the latest research on Kennedy's Disease. To watch the video, click here.
July 13, 2016 - Defects in Neuromuscular Transmission May Underlie Motor Dysfunction in Spinal and Bulbar Muscular Atrophy. To read the article, click here.
July 1, 2016 - Glycolytic-to-oxidative fiber-type switch and mTOR signaling activation are early-onset features of SBMA muscle modified by high-fat diet. To read the article, click here.
June 15, 2016 - Discovery of molecular protection linked to Kennedy’s disease. Scientists from IRB Barcelona have described a molecular system of protection that involves the androgen receptor protein, a molecule that is mutated in patients with Kennedy’s disease and which cause progressive muscle wastage. To read the article, click here.
May 6, 2016 - Michigan State University researchers used an old-fashioned neurobiology technique to explore new avenues for treatments to reverse Kennedy's disease. To read the article, click here. To read the abstract 'Defects in Neuromuscular Transmission May Underlie Motor Dysfunction in Spinal and Bulbar Muscular Atrophy' published in the Journal of Neuroscience, click here.
April 26, 2016 - Although JAMA Neurology published the following article in 2012, Molecular Pathophysiology and Disease-Modifying Therapies for Spinal and Bulbar Muscular Atrophy, the research information was just recently added this year to our Research Update archives. The paper does a good job of explaining Kennedy's Disease to the layperson. To view the article click here.
January 4, 2016 - Gene editing spurs hope for muscular dystrophy cure. For the first time, a breakthrough technique called CRISPR has been used to treat a genetic disease inside a living mammal. Click here to read the article.